HOLLYWOOD, Calif. — Jude Law and Sienna Miller have called it quits again.

The actor's rep confirmed the split Tuesday, telling People magazine they "are no longer in a relationship."

Law, 38, and Miller, 29, have a storied history together. They became engaged in 2004, only to break up two years later after the Cold Mountain star admitted to cheating on the actress with his children's nanny.

The twosome went on to reconcile in the fall of 2009 and have been together ever since.

"It is mutual and amicable and they are still friends," a friend of Law's told the mag of the latest split. "It was an entirely an end-of-the relationship decision. It had run its course."

Law has two sons and a daughter with his ex-wife, actress Sadie Frost. He also has a daughter with model Samantha Burke.

Also see: Jude Law Photos and Sienna Miller Photos